Led by Timoteo, the Vongola Nono, all the members of this generation appear to be beyond their fifties, and it is possible that they are the longest-lasting generation. Possibly due to their old ages, Timoteo sought out their successors, the Vongola Decimo & Guardians, who are to succeed them sometime in the future.
- All of the Guardians' names are in some way derived from desserts, confectionaries, or candies:
- Coyote Nougat refers to nougat.
- Schnitten Brabanters refers to Belgian chocolates and cake.
- Brow Nie Jr. refers to brownies.
- Visconti refers to biscotti.
- Ganauche III refers to ganache.
- Croquant Bouche refers to a dessert consisting of Choux pastry balls piled into a cone.